Biology of multiple endocrine neoplasia type 1
Recent publications
Yanan Cao, Ruixin Liu, Xiuli Jiang, Jieli Lu, Changxian Zhang, Xiaoying Li and Guang Ning Menin suppresses Wnt/β-catenin signaling by the nuclear export mechanism. In preparation.
Jiang XH, Lu JL, Cui B, Zhao YJ, Liu JM, Fang WQ, Cao YN, Ge Y, Zhang CX, Casse H, Li XY, Ning G. Mutation and loss of heterozygosity analysis of MEN1 gene in Chinese patients with multiple endocrine neoplasia type 1. Endocrine Related Cancer. 2007,14(4):1073-1079
Yang J, Cui B, Sun SY, Shi TL, Zheng SY, Bi YF, Liu JM, Zhao YJ, Chen JL, Ning G, Li XY. Phenotype-Genotype Correlation in 8 Chinese 17-hydroxylase/17,20 lyase Deficiency Patients With 5 Novel Mutations of CYP17A1 Gene. Journal of Clinical Endocrinology and Metabolism 2006;91(9):3619-25.(corresponding author)
Fontaniere S, B Duvillié, R Scharfmann, N Hussein, Z-I Wang And C-X Zhang. Tumor suppressor menin is essential for development of the pancreatic endocrine cells. Journal of Endocrinology, 199 : 287-298, 2008.
Nader Hussein, JieLi Lu1, Huguette Casse, Sandra Fontanière, Alain Calender, Nathalie Di Clemente and Chang X. Zhang. Deregulation of AMH/BMP and TGFbeta pathways in Leydig cell lesions developed in male heterozygous Men1 mutant mice. Endocrine-related cancer, 15 : 217-227, 2008.
Nader Hussein, Huguette Casse, Sandra Fontanière, Anne-Marie Morera, Marie J. Asensio, Skander Bakeli, Jie L Lu. et al. European Journal of Cancer, 43:402-414. 2007.
Zhou Y, Zhao Y, Cui B, Gu L, Zhu S, Li J, Liu J, Yin M, Zhao T, Yin Z, Yu C, Chen C, Wang L, Xiao B, Hong J, Zhang Y, Tang Z, Wang S, Li XY, Ning G. RET proto-oncogene mutations are restricted to codons 634 and 918 in mainland Chinese families with MEN2A and MEN2B. Clin Endocrinol (Oxf) 2007;67(4):570-6
Fontaniere S, J Tost, A Wierinckx, J Lachuer, JieLi LU, Z-Q Wang And C-X Zhang. Gene expression profiling in insulinomas developed in Men1 β-cell mutant mice highlights early genetic and epigenetic factors involved in ߖcell tumorigenesis. Endocrine-Related Cancer, 13:1223-1236. 2006.
Pierre J. Zindy, Annie L'Helgoualc'h, Dominique Bonnier, Antony Le Béchec, Katia Bourd-Boitin, Chang Xian Zhang, Orlando Musso, Denise Glaise, Marie Bérangère Troadec, Olivier Loréal, Bruno Turlin, Jean Léger, Bruno Clément, Nathalie Théret. 2006, Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis. Hepathology, 44(5):1296 - 1307. 2006.
Fontanière S, Casse H, Bertolino P and Zhang CX Analysis of p27Kip1 expression in insulinomas developed in pancreatic β-cell specific Men1 mutant mice. Familial Cancer, 5:49-54, 2006.
