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Research Topics



Team members

Team publications

French Partner 1
French Principal Investigator 1
Pr. Brigitte GICQUEL

French Partner 2
French Principal Investigator 2
Dr. Olivier NEYROLLES

Chinese Partner
Chinese Principal Investigator
Pr. ZHANG Ji
张济 教授
Team 1Team 2Team 3Team 4Team 5Team 6Team 7

Mycobacterium tuberculosis genetic diversity
and host-pathogen interactions

Recent publications

Dos Vultos T, Mestre O, Rauzier J, Golec M, Rastogi N, Rasolofo V, Tonjum T, Sola C, Matic I, Gicquel B. 2008 Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis. PLoS ONE 3(2):e1538

Tailleux L, Waddell SJ, Pellizola M, Mortellaro A, Withers M, Tanne A, Ricciardi Castagnoli P, Gicquel B, Stoker NG, Butcher PD, Foti M & Neyrolles O. 2008 Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. PLoS ONE 3:e1403

Becq J, Gutierrez MC, Rosas-Magallanes V, Rauzier J, Gicquel B, Neyrolles O & Deschavanne P. 2007 Contribution of horizontally acquired genomic islands to the evolution of the tubercle bacilli. Mol Biol Evol 24:1861-71

Tailleux L, Pham-Thi N, Bergeron-Lafaurie A, Herrmann JL, Charles P, Schwartz O, Scheinmann P, Lagrange PH, de Blic J, Tazi A, Gicquel B & Neyrolles O. 2005 DC-SIGN induction in alveolar macrophages defines a privileged target host cell population for mycobacteria in patients with tuberculosis. PLoS Med 2:e381

Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B & Neyrolles O. 2003 DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J Exp Med 197: 121-7